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GENE - TERM ANNOTATION REPORT

RGD ID: 1323770
Species: Homo sapiens
RGD Object: Gene
Symbol: SHMT1
Name: serine hydroxymethyltransferase 1
Acc ID: GO:0030170
Term: pyridoxal phosphate binding
Definition: Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
Definition Source(s): GOC:mah, ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SHMT1 ISOShmt1 (Rattus norvegicus)9068941RGD PMID:3110140 REF_RGD_ID:2300383
SHMT1enablesIBAPANTHER:PTN000188065 or Shmt2 (Rattus norvegicus) or Shmt1 (Rattus norvegicus) or UniProtKB:P0A825 or UniProtKB:P34896 or UniProtKB:P34897 or UniProtKB:P9WGI7 or UniProtKB:P9WGI9 or ZFIN:ZDB-GENE-071213-1150520179GO_Central GO_REF:0000033
SHMT1enablesIEAInterPro:IPR001085 or InterPro:IPR019798150520179InterPro GO_REF:0000002
SHMT1enablesIEAPANTHER:PTHR11680:SF35150520179TreeGrafter GO_REF:0000118
SHMT1enablesIDA 150520179UniProt PMID:17482557 PMID:24698160

PMID:17482557 PMID:24698160
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