GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ACIN1 | affects methylation | EXP | | 6480464 | CTD | Benzo(a)pyrene affects the methylation of ACIN1 promoter | PMID:27901495 | ACIN1 | increases expression | ISO | Acin1 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of ACIN1 mRNA | PMID:14625279 PMID:22228805 | ACIN1 | multiple interactions | ISO | Acin1 (Mus musculus) | 6480464 | CTD | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ACIN1 mRNA; [Potassium Dichromate co-treated with potassium chromate(VI)] inhibits the reaction [Benzo(a)pyrene results in increased expression of ACIN1 mRNA]; Benzo(a)pyrene promotes the reaction [AHR protein binds to ACIN1 promoter] | PMID:14625279 PMID:19654925 PMID:27858113 | |
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