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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1323633
Species: Mus musculus
RGD Object: Gene
Symbol: Chd3
Name: chromodomain helicase DNA binding protein 3
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chd3affects expressionISOCHD3 (Homo sapiens)6480464CTDValproic Acid affects the expression of CHD3 mRNAPMID:25979313
Chd3affects splicingISOChd3 (Rattus norvegicus)6480464CTDValproic Acid affects the splicing of CHD3 mRNAPMID:29427782
Chd3decreases expressionISOCHD3 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of CHD3 mRNAPMID:23179753 PMID:27188386 PMID:29154799
Chd3decreases methylationISOCHD3 (Homo sapiens)6480464CTDValproic Acid results in decreased methylation of CHD3 genePMID:29154799
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