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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1323305
Species: Mus musculus
RGD Object: Gene
Symbol: Bub1
Name: BUB1, mitotic checkpoint serine/threonine kinase
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bub1decreases expressionISOBUB1 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of BUB1 mRNAPMID:23179753 PMID:24935251 PMID:27188386
Bub1increases expressionISOBUB1 (Homo sapiens)6480464CTDValproic Acid results in increased expression of BUB1 mRNAPMID:19101580
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