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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322461
Species: Homo sapiens
RGD Object: Gene
Symbol: IL33
Name: interleukin 33
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL33increases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of IL33 mRNAPMID:35811015
IL33increases secretionEXP 6480464CTDLipopolysaccharides results in increased secretion of IL33 proteinPMID:29673796
IL33multiple interactionsEXP 6480464CTD[Lipopolysaccharides co-treated with 2,3-bis(4-hydroxyphenyl)-propionitrile] results in increased expression of IL33 protein; [Lipopolysaccharides co-treated with 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol] results in increased expression of IL33 protein; [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of IL33 mRNA; [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of IL33 mRNA; Nicotine promotes the reaction [Lipopolysaccharides results in increased secretion of IL33 protein]; Tobacco Smoke Pollution promotes the reaction [Lipopolysaccharides results in increased secretion of IL33 protein]PMID:29673796 PMID:30445053 PMID:35811015
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