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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322126
Species: Homo sapiens
RGD Object: Gene
Symbol: MEF2A
Name: myocyte enhancer factor 2A
Acc ID: CHEBI:20993
Term: aldehydo-D-glucosamine
Definition: The open-chain form of D-glucosamine.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MEF2Adecreases expressionEXP 6480464CTDGlucosamine results in decreased expression of MEF2A mRNA; Glucosamine results in decreased expression of MEF2A proteinPMID:20165829
MEF2Amultiple interactionsEXP 6480464CTD4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]PMID:20165829
MEF2Adecreases expressionISOMef2a (Rattus norvegicus)6480464CTDGlucosamine results in decreased expression of MEF2A mRNA; Glucosamine results in decreased expression of MEF2A proteinPMID:20165829
MEF2Amultiple interactionsISOMef2a (Rattus norvegicus)6480464CTD4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]PMID:20165829
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