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GENE - TERM ANNOTATION REPORT

RGD ID: 1321964
Species: Homo sapiens
RGD Object: Gene
Symbol: USPL1
Name: ubiquitin specific peptidase like 1
Acc ID: GO:0015030
Term: Cajal body
Definition: A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
Definition Source(s): NIF_Subcellular:nlx_subcell_090901, PMID:10944589, PMID:11031238, PMID:7559785
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
USPL1is_active_inIBAPANTHER:PTN001033803 or UniProtKB:Q5W0Q7 or ZFIN:ZDB-GENE-040930-7150520179GO_Central GO_REF:0000033
USPL1located_inIEAPANTHER:PTHR15294:SF3150520179TreeGrafter GO_REF:0000118
USPL1located_inIDA 150520179UniProt PMID:22878415 PMID:24413172

PMID:22878415 PMID:24413172
USPL1located_inIEAUniProtKB-SubCell:SL-0031150520179UniProt GO_REF:0000044
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