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GENE - TERM ANNOTATION REPORT

RGD ID: 1321815
Species: Homo sapiens
RGD Object: Gene
Symbol: NDUFB3
Name: NADH:ubiquinone oxidoreductase subunit B3
Acc ID: GO:0005747
Term: mitochondrial respiratory chain complex I
Definition: A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
Definition Source(s): GOC:mtg_sensu, ISBN:0198547684
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NDUFB3located_inIPI 150520179ComplexPortal PMID:28844695

PMID:28844695
NDUFB3part_ofIBAFB:FBgn0034645 or PANTHER:PTN001031099 or TAIR:locus:2065243 or UniProtKB:O43676 or UniProtKB:Q02365150520179GO_Central GO_REF:0000033
NDUFB3part_ofIEAPANTHER:PTHR15082:SF2150520179TreeGrafter GO_REF:0000118
NDUFB3part_ofIDA 150520179UniProt PMID:12611891 PMID:27626371

PMID:12611891 PMID:27626371
NDUFB3part_ofNAS 150520179UniProt PMID:9878551

PMID:9878551
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