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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321618
Species: Homo sapiens
RGD Object: Gene
Symbol: ITGAV
Name: integrin subunit alpha V
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ITGAVmultiple interactionsEXP 6480464CTD[Plant Extracts co-treated with Resveratrol] results in increased expression of ITGAV mRNA; Resveratrol promotes the reaction [[ITGAV protein binds to ITGB3 protein] which affects the localization of FYN protein]; Resveratrol promotes the reaction [[ITGAV protein binds to ITGB3 protein] which affects the localization of GRB2 protein]; Resveratrol promotes the reaction [[ITGAV protein binds to ITGB3 protein] which affects the localization of PTK2 protein]; Resveratrol promotes the reaction [[ITGAV protein binds to ITGB3 protein] which affects the localization of SOS1 protein]PMID:21467134 PMID:23557933
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