GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Srf | decreases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of SRF mRNA | PMID:19770486 PMID:21715664 PMID:22228805 | Srf | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of SRF mRNA | PMID:22228805 | Srf | multiple interactions | EXP | | 6480464 | CTD | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of SRF mRNA] | PMID:22228805 | Srf | affects activity | ISO | SRF (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the activity of SRF protein | PMID:20624995 | Srf | decreases methylation | ISO | SRF (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of SRF promoter | PMID:27901495 | Srf | increases expression | ISO | Srf (Rattus norvegicus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of SRF protein | PMID:21467743 | |
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