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GENE - TERM ANNOTATION REPORT

RGD ID: 1320489
Species: Homo sapiens
RGD Object: Gene
Symbol: HLCS
Name: holocarboxylase synthetase
Acc ID: GO:0004077
Term: biotin-[acetyl-CoA-carboxylase] ligase activity
Definition: Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)).
Definition Source(s): EC:6.3.4.15
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HLCSenablesIBACGD:CAL0000192734 or PANTHER:PTN000303161 or SGD:S000002300 or TAIR:locus:2050291 or UniProtKB:C6S3D7 or UniProtKB:P06709150520179GO_Central GO_REF:0000033
HLCSenablesIEAInterPro:IPR004408150520179InterPro GO_REF:0000002
HLCSenablesIEARHEA:11756150520179RHEA GO_REF:0000116
HLCSenablesIEAEC:6.3.4.15150520179UniProt GO_REF:0000003
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