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GENE - TERM ANNOTATION REPORT

RGD ID: 1320402
Species: Mus musculus
RGD Object: Gene
Symbol: Trem2
Name: triggering receptor expressed on myeloid cells 2
Acc ID: GO:0030316
Term: osteoclast differentiation
Definition: The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
Definition Source(s): CL:0000092, GOC:add, ISBN:0781735149, PMID:12161749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trem2acts_upstream_of_or_withinISOUniProtKB:Q9NZC22290270MGI PMID:21841309

PMID:21841309
Trem2involved_inISOUniProtKB:Q9NZC22290270MGI GO_REF:0000119 MGI:4834177
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