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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320331
Species: Mus musculus
RGD Object: Gene
Symbol: Hdac1
Name: histone deacetylase 1
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hdac1multiple interactionsISOHDAC1 (Homo sapiens)6480464CTDDecitabine inhibits the reaction [HDAC1 protein binds to ABCG2 promoter]; Decitabine inhibits the reaction [HDAC1 protein binds to BUB1B promoter]; Decitabine inhibits the reaction [HDAC1 protein binds to CDKN1A promoter]PMID:16043219 PMID:16954373 PMID:17464181
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