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GENE - TERM ANNOTATION REPORT

RGD ID: 1320052
Species: Homo sapiens
RGD Object: Gene
Symbol: TDP1
Name: tyrosyl-DNA phosphodiesterase 1
Acc ID: GO:0017005
Term: 3'-tyrosyl-DNA phosphodiesterase activity
Definition: Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.
Definition Source(s): PMID:10521354, PMID:16751265
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TDP1enablesIBAFB:FBgn0260817 or PANTHER:PTN000275870 or PomBase:SPCP31B10.05 or SGD:S000000427 or TAIR:locus:2150931 or UniProtKB:Q9NUW8150520179GO_Central GO_REF:0000033
TDP1enablesIEAPANTHER:PTHR12415:SF0150520179TreeGrafter GO_REF:0000118
TDP1enablesIDA 150520179UniProt PMID:17118488 PMID:17576665 PMID:17948061 PMID:22822062

PMID:17118488 PMID:17576665 PMID:17948061 PMID:22822062
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