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GENE - TERM ANNOTATION REPORT

RGD ID: 1319609
Species: Mus musculus
RGD Object: Gene
Symbol: Ltk
Name: leukocyte tyrosine kinase
Acc ID: GO:0007169
Term: cell surface receptor protein tyrosine kinase signaling pathway
Definition: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:ceb, GOC:signaling
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ltkinvolved_inIBAPANTHER:PTN001230349 or Erbb3 (Rattus norvegicus) or UniProtKB:A0A2R8QHE8 or UniProtKB:Q9UM73 or UniProtKB:Q15303 or Fgfr2 (Rattus norvegicus) or MGI:96683 or Erbb2 (Rattus norvegicus) or MGI:96575 or FB:FBgn0003366 or MGI:95524 or UniProtKB:Q08345 or MGI:97384 or ZFIN:ZDB-GENE-980526-326 or UniProtKB:P22607 or FB:FBgn0003731 or MGI:104757 or UniProtKB:P10721 or MGI:1339758 or UniProtKB:P16234 or MGI:97531 or UniProtKB:P54760 or FB:FBgn0003733 or MGI:95522 or Erbb4 (Rattus norvegicus) or FB:FBgn0040505 or MGI:95278 or FB:FBgn0010389 or UniProtKB:P06213 or MGI:95523 or ZFIN:ZDB-GENE-980526-255 or UniProtKB:P21860 or UniProtKB:Q02763 or Fgfr3 (Rattus norvegicus) or UniProtKB:Q16832 or Fgfr4 (Rattus norvegicus) or UniProtKB:P29317 or Ddr1 (Rattus norvegicus) or UniProtKB:P04626 or MGI:95410 or FB:FBgn0283499 or UniProtKB:P00533 or MGI:95294 or UniProtKB:A6QR62 or UniProtKB:P07949 or ZFIN:ZDB-GENE-990415-62 or UniProtKB:Q16288 or MGI:1345277 or FB:FBgn0032006 or MGI:99216 or Ntrk2 (Rattus norvegicus) or UniProtKB:P21802 or Egfr (Rattus norvegicus) or Kdr (Rattus norvegicus) or WB:WBGene00002299 or UniProtKB:P35968 or Igf1r (Rattus norvegicus) or MGI:95411 or ZFIN:ZDB-GENE-020503-2 or MGI:95525 or ZFIN:ZDB-GENE-020503-1 or UniProtKB:P08069 or UniProtKB:P29376 or MGI:97902 or UniProtKB:P09619 or Flt4 (Rattus norvegicus) or ZFIN:ZDB-GENE-060503-14 or MGI:95558 or Insr (Rattus norvegicus) or UniProtKB:P35916 or UniProtKB:Q16620 or UniProtKB:P04629 or MGI:96969 or FB:FBgn0285896 or UniProtKB:P22455 or MGI:104771 or UniProtKB:P11362 or ZFIN:ZDB-GENE-070713-2 or MGI:99654 or WB:WBGene00001184 or UniProtKB:P17948 or MGI:96433 or MGI:975302290270GO_Central GO_REF:0000033
Ltkinvolved_inISOUniProtKB:P293762290270MGI GO_REF:0000119 MGI:4834177
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