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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319126
Species: Mus musculus
RGD Object: Gene
Symbol: Eif3b
Name: eukaryotic translation initiation factor 3, subunit B
Acc ID: CHEBI:17148
Term: putrescine
Definition: A four-carbon alkane-alpha,omega-diamine. It is obtained by the breakdown of amino acids and is responsible for the foul odour of putrefying flesh.
Chemical ID: MESH:D011700
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif3bmultiple interactionsISOEif3b (Rattus norvegicus)6480464CTD[ODC1 protein results in increased abundance of Putrescine] which results in decreased expression of EIF3B protein; Pentanoic Acids inhibits the reaction [[ODC1 protein results in increased abundance of Putrescine] which results in decreased expression of EIF3B protein]; Putrescine inhibits the reaction [Pentanoic Acids results in increased expression of EIF3B protein]PMID:22555848
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