GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CSK | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of CSK mRNA | PMID:21802500 PMID:23152189 | CSK | affects expression | ISO | Csk (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of CSK mRNA | PMID:22298810 PMID:34747641 | CSK | increases expression | ISO | Csk (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of CSK mRNA | PMID:18796159 PMID:33387578 | CSK | increases response to substance | ISO | Csk (Mus musculus) | 6480464 | CTD | CSK protein results in increased susceptibility to Tetrachlorodibenzodioxin | PMID:9664232 | CSK | multiple interactions | ISO | Csk (Mus musculus) | 6480464 | CTD | CSK protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]]; CSK protein promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine binds to THRA protein]]; CSK protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of FOS protein]; CSK protein promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CSK protein promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; geldanamycin inhibits the reaction [CSK protein results in increased susceptibility to Tetrachlorodibenzodioxin]; geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CSK protein binds to AHR protein]]; Tetrachlorodibenzodioxin promotes the reaction [CSK protein binds to AHR protein] | PMID:9664232 | |
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