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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318666
Species: Homo sapiens
RGD Object: Gene
Symbol: SERPINB9
Name: serpin family B member 9
Acc ID: CHEBI:34857
Term: Moxestrol
Definition: A 3-hydroxy steroid that has formula C21H26O3.
Chemical ID: MESH:C011310
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SERPINB9increases expressionEXP 6480464CTDmoxestrol results in increased expression of SERPINB9 mRNA; moxestrol results in increased expression of SERPINB9 proteinPMID:10681578 PMID:12177049 PMID:14617632
SERPINB9multiple interactionsEXP 6480464CTDCycloheximide promotes the reaction [moxestrol results in increased expression of SERPINB9 mRNA]; fulvestrant inhibits the reaction [moxestrol results in increased expression of SERPINB9 mRNA]; IL1B protein inhibits the reaction [moxestrol results in increased expression of SERPINB9 mRNA]; moxestrol promotes the reaction [ESR1 protein binds to SERPINB9 protein]; Tamoxifen analog inhibits the reaction [moxestrol results in increased expression of SERPINB9 mRNA]PMID:10681578 PMID:12177049 PMID:14617632
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