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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318015
Species: Mus musculus
RGD Object: Gene
Symbol: Nlrp3
Name: NLR family, pyrin domain containing 3
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nlrp3multiple interactionsISONlrp3 (Rattus norvegicus)6480464CTD[dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of NLRP3 mRNA]; [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of NLRP3 protein]; [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of NLRP3 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of NLRP3 protein; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NLRP3 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NLRP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein; diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NLRP3 mRNA]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NLRP3 protein]PMID:26464617 PMID:33729688 PMID:35191607
Nlrp3multiple interactionsISONLRP3 (Homo sapiens)6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein; bellidifolin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein]PMID:37127800
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