GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nlrp3 | multiple interactions | ISO | Nlrp3 (Rattus norvegicus) | 6480464 | CTD | [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of NLRP3 mRNA]; [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of NLRP3 protein]; [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of NLRP3 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of NLRP3 protein; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NLRP3 mRNA; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NLRP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein; diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NLRP3 mRNA]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NLRP3 protein] | PMID:26464617 PMID:33729688 PMID:35191607 | Nlrp3 | multiple interactions | ISO | NLRP3 (Homo sapiens) | 6480464 | CTD | [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein; bellidifolin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NLRP3 protein] | PMID:37127800 | |
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