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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317968
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC30A8
Name: solute carrier family 30 member 8
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC30A8multiple interactionsEXP 6480464CTDSLC30A8 protein promotes the reaction [Glucose results in increased secretion of INS protein]PMID:16984975
SLC30A8decreases expressionISOSlc30a8 (Rattus norvegicus)6480464CTDGlucose results in decreased expression of SLC30A8; Glucose results in decreased expression of SLC30A8 mRNAPMID:19492079 PMID:23056475
SLC30A8multiple interactionsISOSlc30a8 (Rattus norvegicus)6480464CTD[Glucose co-treated with dihydroxyethyldithiocarbamate] results in decreased expression of SLC30A8; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Glucose results in decreased expression of SLC30A8 mRNA]; SLC30A8 protein affects the reaction [Glucose results in increased secretion of INS1 protein]PMID:19479076 PMID:19492079 PMID:23056475
SLC30A8multiple interactionsISOSlc30a8 (Mus musculus)6480464CTDSLC30A8 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]PMID:19450229
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