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GENE - TERM ANNOTATION REPORT

RGD ID: 1317897
Species: Mus musculus
RGD Object: Gene
Symbol: Rorc
Name: RAR-related orphan receptor gamma
Acc ID: GO:0072539
Term: T-helper 17 cell differentiation
Definition: The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
Definition Source(s): CL:0000899, GOC:BHF, GOC:ebc
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rorcinvolved_inIMP 2290270GO_Central MGI:3692468 PMID:16990136 MGI:3772713 PMID:18164222

MGI:3692468 MGI:3772713 PMID:16990136 PMID:18164222
Rorcacts_upstream_of_or_withinIDA 2290270MGI PMID:18792410

PMID:18792410
Rorcinvolved_inIMPMGI:23861142290270MGI PMID:20383124

PMID:20383124
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