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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317606
Species: Homo sapiens
RGD Object: Gene
Symbol: WNT3A
Name: Wnt family member 3A
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
WNT3Adecreases expressionISOWnt3a (Mus musculus)6480464CTDStreptozocin results in decreased expression of WNT3A proteinPMID:34428446
WNT3Amultiple interactionsISOWnt3a (Mus musculus)6480464CTD5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein]PMID:34428446
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