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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317388
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP1
Name: matrix metallopeptidase 1
Acc ID: CHEBI:35807
Term: N-nitrosodimethylamine
Definition: A nitrosamine that has formula C2H6N2O.
Chemical ID: MESH:D004128
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP1increases expressionISOMmp1 (Rattus norvegicus)6480464CTDDimethylnitrosamine results in increased expression of MMP1 mRNAPMID:16270385
MMP1multiple interactionsISOMmp1 (Rattus norvegicus)6480464CTDDrugs, Chinese Herbal inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA]; Flavonoids inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA]; Plant Preparations inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP1 mRNA]PMID:16270385
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