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GENE - TERM ANNOTATION REPORT

RGD ID: 1316352
Species: Homo sapiens
RGD Object: Gene
Symbol: ELOVL3
Name: ELOVL fatty acid elongase 3
Acc ID: GO:0009922
Term: fatty acid elongase activity
Definition: Catalysis of the reaction: a very-long-chain acyl-CoA + H+ + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA. This reaction is the first (condensation) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.
Definition Source(s): PMID:16564093, PMID:19763486, RHEA:32727
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ELOVL3enablesIBAFB:FBgn0037762 or FB:FBgn0052072 or FB:FBgn0260942 or FB:FBgn0260960 or MGI:1858960 or MGI:1933331 or PANTHER:PTN000125390 or PomBase:SPAC1B2.03c or Elovl5 (Rattus norvegicus) or Elovl6 (Rattus norvegicus) or SGD:S000000630 or SGD:S000003732 or SGD:S000004364 or TAIR:locus:2115395 or UniProtKB:A1L3X0 or UniProtKB:E1BYE9 or UniProtKB:E3VVZ8 or UniProtKB:K0H6Z1 or UniProtKB:Q57UP6 or UniProtKB:Q57UP7 or UniProtKB:Q57UP8 or UniProtKB:Q57X51 or UniProtKB:Q9BW60 or UniProtKB:Q9H5J4 or UniProtKB:Q9HB03 or UniProtKB:Q9NXB9 or UniProtKB:Q9NYP7 or ZFIN:ZDB-GENE-040407-2 or dictyBase:DDB_G0292896150520179GO_Central GO_REF:0000033
ELOVL3enablesIEAInterPro:IPR002076 or InterPro:IPR033679150520179InterPro GO_REF:0000002
ELOVL3enablesEXP 150520179Reactome PMID:10970790

PMID:10970790
ELOVL3enablesIEARHEA:32727150520179RHEA GO_REF:0000116
ELOVL3enablesTAS 150520179Reactome Reactome:R-HSA-548814
ELOVL3enablesIEAPANTHER:PTHR11157:SF68150520179TreeGrafter GO_REF:0000118
ELOVL3enablesIEAEC:2.3.1.199150520179UniProt GO_REF:0000003
ELOVL3enablesIEAUniRule:UR000254920150520179UniProt GO_REF:0000104
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