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GENE - TERM ANNOTATION REPORT

RGD ID: 1316169
Species: Mus musculus
RGD Object: Gene
Symbol: Mrpl2
Name: mitochondrial ribosomal protein L2
Acc ID: GO:0005840
Term: ribosome
Definition: An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mrpl2located_inIEAInterPro:IPR002171 or InterPro:IPR022669 or InterPro:IPR0226662290270UniProt GO_REF:0000002 MGI:2152098
Mrpl2located_inIEAUniProtKB-KW:KW-06892290270UniProt GO_REF:0000043 MGI:1354194
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