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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315668
Species: Homo sapiens
RGD Object: Gene
Symbol: STIM1
Name: stromal interaction molecule 1
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STIM1increases expressionISOStim1 (Rattus norvegicus)6480464CTDGlucose results in increased expression of STIM1 mRNA; Glucose results in increased expression of STIM1 proteinPMID:27234048
STIM1multiple interactionsISOStim1 (Rattus norvegicus)6480464CTDSTIM1 protein affects the reaction [Glucose results in decreased expression of BCL2 protein]; STIM1 protein affects the reaction [Glucose results in increased cleavage of CASP3 protein]; STIM1 protein affects the reaction [Glucose results in increased expression of BAX protein]PMID:27234048
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