GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SLC39A4 | affects expression | EXP | | 6480464 | CTD | Zinc affects the expression of SLC39A4 protein | PMID:20479680 | SLC39A4 | decreases expression | EXP | | 6480464 | CTD | Zinc results in decreased expression of SLC39A4 mRNA; Zinc results in decreased expression of SLC39A4 protein | PMID:15753530 PMID:17202136 | SLC39A4 | increases transport | EXP | | 6480464 | CTD | SLC39A4 protein results in increased transport of Zinc | PMID:18326752 | SLC39A4 | increases uptake | EXP | | 6480464 | CTD | SLC39A4 protein results in increased uptake of Zinc | PMID:17202136 | SLC39A4 | multiple interactions | EXP | | 6480464 | CTD | Ammonium Chloride inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein]; methyl-beta-cyclodextrin inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein]; Sucrose inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein]; Zinc results in increased ubiquitination of and results in increased degradation of SLC39A4 protein | PMID:17202136 | SLC39A4 | affects expression | ISO | Slc39a4 (Mus musculus) | 6480464 | CTD | Zinc affects the expression of SLC39A4 mRNA | PMID:16682017 | SLC39A4 | affects localization | ISO | Slc39a4 (Mus musculus) | 6480464 | CTD | Zinc affects the localization of SLC39A4 protein; Zinc deficiency affects the localization of SLC39A4 protein | PMID:12801924 PMID:14709598 PMID:15358787 | SLC39A4 | decreases expression | ISO | Slc39a4 (Mus musculus) | 6480464 | CTD | Zinc deficiency results in decreased expression of SLC39A4 mRNA; Zinc results in decreased expression of SLC39A4 mRNA; Zinc results in decreased expression of SLC39A4 protein | PMID:12514265 PMID:12801924 PMID:17202136 PMID:18020946 | SLC39A4 | increases expression | ISO | Slc39a4 (Mus musculus) | 6480464 | CTD | Zinc deficiency results in increased expression of SLC39A4 mRNA; Zinc deficiency results in increased expression of SLC39A4 protein | PMID:12801924 PMID:15358787 PMID:18020946 | SLC39A4 | increases response to substance | ISO | Slc39a4 (Mus musculus) | 6480464 | CTD | SLC39A4 gene mutant form results in increased susceptibility to Zinc deficiency | PMID:17483098 | SLC39A4 | increases uptake | ISO | Slc39a4 (Mus musculus) | 6480464 | CTD | SLC39A4 protein results in increased uptake of Zinc | PMID:12801924 PMID:14709598 PMID:15322118 | SLC39A4 | multiple interactions | ISO | Slc39a4 (Mus musculus) | 6480464 | CTD | Cycloheximide inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA]; Cycloheximide inhibits the reaction [Zinc results in decreased expression of SLC39A4 mRNA]; Dactinomycin inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA]; Dactinomycin inhibits the reaction [Zinc results in decreased expression of SLC39A4 mRNA]; Zinc affects the localization of and results in increased degradation of SLC39A4 protein; Zinc deficiency results in increased expression of and results in increased stability of SLC39A4 mRNA; Zinc inhibits the reaction [Zinc deficiency results in increased expression of and results in increased stability of SLC39A4 mRNA]; Zinc inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA]; Zinc inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 protein] | PMID:12801924 PMID:18020946 | |
Go Back to source page | Continue to Ontology report |