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GENE - TERM ANNOTATION REPORT

RGD ID: 1315377
Species: Mus musculus
RGD Object: Gene
Symbol: Dot1l
Name: DOT1 like histone lysine methyltransferase
Acc ID: GO:0031151
Term: histone H3K79 methyltransferase activity
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group to the lysine residue at position 79 of the histone H3 protein.
Definition Source(s): GOC:mah, PMID:15371351
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dot1lenablesIBAPANTHER:PTN000485246 or FB:FBgn0264495 or SGD:S000002848 or dictyBase:DDB_G02716262290270GO_Central GO_REF:0000033
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