GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IGFBP7 | affects methylation | EXP | | 6480464 | CTD | Benzo(a)pyrene affects the methylation of IGFBP7 promoter | PMID:27901495 | IGFBP7 | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of IGFBP7 mRNA | PMID:20106945 PMID:21632981 PMID:22316170 PMID:32234424 | IGFBP7 | decreases expression | ISO | Igfbp7 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of IGFBP7 mRNA | PMID:15034205 | IGFBP7 | increases expression | ISO | Igfbp7 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of IGFBP7 mRNA | PMID:22228805 | IGFBP7 | multiple interactions | ISO | Igfbp7 (Mus musculus) | 6480464 | CTD | AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of IGFBP7 mRNA] | PMID:15034205 | |
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