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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314662
Species: Homo sapiens
RGD Object: Gene
Symbol: IVL
Name: involucrin
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IVLdecreases expressionEXP 6480464CTDTretinoin analog results in decreased expression of IVL mRNA; Tretinoin results in decreased expression of IVL mRNAPMID:1318502 PMID:17214633
IVLincreases expressionEXP 6480464CTDTretinoin results in increased expression of IVL mRNA; Tretinoin results in increased expression of IVL proteinPMID:16249480 PMID:17034753 PMID:25240866 PMID:8396608 PMID:9716179
IVLmultiple interactionsEXP 6480464CTDTretinoin inhibits the reaction [IL1A protein results in increased expression of IVL mRNA]PMID:17214633
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