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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313655
Species: Homo sapiens
RGD Object: Gene
Symbol: TTK
Name: TTK protein kinase
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TTKaffects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of TTK promoterPMID:27901495
TTKdecreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of TTK mRNAPMID:16120219 PMID:20064835 PMID:21632981
TTKincreases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of TTK mRNAPMID:33411230
TTKdecreases expressionISOTtk (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of TTK mRNAPMID:19770486
TTKdecreases methylationISOTtk (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased methylation of TTK intronPMID:27901495
TTKincreases expressionISOTtk (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of TTK mRNAPMID:32417428
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