GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ATF6 | increases expression | EXP | | 6480464 | CTD | Glucosamine results in increased expression of ATF6 mRNA | PMID:19383982 PMID:20165829 PMID:33812996 | ATF6 | multiple interactions | EXP | | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] | PMID:20165829 PMID:33812996 | ATF6 | decreases expression | ISO | Atf6 (Mus musculus) | 6480464 | CTD | Glucosamine results in decreased expression of ATF6 mRNA | PMID:17178593 | ATF6 | increases expression | ISO | Atf6 (Rattus norvegicus) | 6480464 | CTD | Glucosamine results in increased expression of ATF6 mRNA | PMID:20165829 | ATF6 | increases expression | ISO | Atf6 (Mus musculus) | 6480464 | CTD | Glucosamine results in increased expression of ATF6 protein | PMID:30602124 | ATF6 | multiple interactions | ISO | Atf6 (Rattus norvegicus) | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] | PMID:20165829 | ATF6 | multiple interactions | ISO | Atf6 (Mus musculus) | 6480464 | CTD | ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA] | PMID:30602124 | |
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