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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313299
Species: Homo sapiens
RGD Object: Gene
Symbol: MDM2
Name: MDM2 proto-oncogene
Acc ID: CHEBI:34204
Term: 2,2',4,4'-tetrachlorobiphenyl
Definition: A tetrachlorobiphenyl that is biphenyl in which each of the phenyl groups is substituted at positions 2 and 4 by chlorines.
Chemical ID: MESH:C035976
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MDM2increases phosphorylationEXP 6480464CTD2,4,2',4'-tetrachlorobiphenyl results in increased phosphorylation of MDM2 proteinPMID:19751709
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