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GENE - TERM ANNOTATION REPORT

RGD ID: 1312693
Species: Homo sapiens
RGD Object: Gene
Symbol: POLD2
Name: DNA polymerase delta 2, accessory subunit
Acc ID: GO:0043625
Term: delta DNA polymerase complex
Definition: A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.
Definition Source(s): GOC:jl, ISBN:0198547684, PMID:11205330, PMID:12403614
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
POLD2 ISOPold2 (Rattus norvegicus)9068941RGD PMID:10541966 REF_RGD_ID:729526
POLD2located_inIPI 150520179ComplexPortal PMID:12403614

PMID:12403614
POLD2part_ofIEAUniProtKB:O35654 or ensembl:ENSMUSP00000099986150520179Ensembl GO_REF:0000107
POLD2part_ofIDA 150520179FlyBase PMID:11595739 PMID:22465957

PMID:11595739 PMID:22465957
POLD2part_ofIBAFB:FBgn0027903 or MGI:1097163 or PANTHER:PTN000045936 or PomBase:SPAC27E2.05 or Pold2 (Rattus norvegicus) or UniProtKB:P49004 or UniProtKB:P49005150520179GO_Central GO_REF:0000033
POLD2part_ofIEAPANTHER:PTHR10416:SF0150520179TreeGrafter GO_REF:0000118
POLD2part_ofIEAARBA:ARBA00028885150520179UniProt GO_REF:0000117
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