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RGD ID: 1312639
Species: Homo sapiens
RGD Object: Gene
Symbol: CDC27
Name: cell division cycle 27
Acc ID: GO:0031145
Term: anaphase-promoting complex-dependent catabolic process
Definition: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
Definition Source(s): GOC:mah, PMID:15380083, PMID:15840442
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAFB:FBgn0012058, PANTHER:PTN000970703, PomBase:SPAC6F12.15c, SGD:S000000180, SGD:S000001209, SGD:S0000015052290271GO_Central (PMID:21873635)

 TAS 2290271Reactome Reactome:R-HSA-174048, Reactome:R-HSA-174143, Reactome:R-HSA-174154, Reactome:R-HSA-174178, Reactome:R-HSA-174184
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.