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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312509
Species: Homo sapiens
RGD Object: Gene
Symbol: HDAC2
Name: histone deacetylase 2
Acc ID: CHEBI:50692
Term: mifepristone
Definition: A 3-oxo steroid that has formula 429.59374.
Chemical ID: MESH:D015735
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HDAC2increases expressionEXP 6480464CTDMifepristone results in increased expression of HDAC2 mRNAPMID:17584828
HDAC2multiple interactionsISOHdac2 (Rattus norvegicus)6480464CTDMifepristone inhibits the reaction [Dexamethasone results in decreased expression of HDAC2 protein]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of HDAC2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of HDAC2 protein]PMID:31518422 PMID:32791177
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