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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312234
Species: Homo sapiens
RGD Object: Gene
Symbol: TNFAIP2
Name: TNF alpha induced protein 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFAIP2affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of TNFAIP2 mRNAPMID:22298810
TNFAIP2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of TNFAIP2 mRNAPMID:19692669
TNFAIP2affects expressionISOTnfaip2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of TNFAIP2 mRNAPMID:18343893 PMID:21570461 PMID:26377647
TNFAIP2affects expressionISOTnfaip2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of TNFAIP2 mRNAPMID:22298810
TNFAIP2increases expressionISOTnfaip2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of TNFAIP2 mRNAPMID:15328365 PMID:15800033 PMID:16611356 PMID:18796159 PMID:19770486 PMID:19933214 PMID:21851831 PMID:21889950 PMID:21995607 PMID:23994337 PMID:26290441
TNFAIP2increases expressionISOTnfaip2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of TNFAIP2 mRNAPMID:33387578
TNFAIP2multiple interactionsISOTnfaip2 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of TNFAIP2 mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TNFAIP2 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of TNFAIP2 mRNA; AHR affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TNFAIP2 mRNA]PMID:16214954 PMID:17942748 PMID:21995607 PMID:25975270
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