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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312115
Species: Mus musculus
RGD Object: Gene
Symbol: Lpin2
Name: lipin 2
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lpin2increases expressionEXP 6480464CTDpirinixic acid results in increased expression of LPIN2 mRNAPMID:17426115 PMID:18301758 PMID:18445702 PMID:19850644 PMID:20813756 PMID:23811191
Lpin2multiple interactionsEXP 6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of LPIN2 mRNA; PPARA protein promotes the reaction [pirinixic acid results in decreased expression of LPIN2 mRNA]PMID:19710929 PMID:19850644
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