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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Acc ID: CHEBI:29320
Term: calcium(0)
Definition: An elemental calcium that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpm2increases transportEXP 6480464CTDTRPM2 protein results in increased transport of CalciumPMID:21900507
Trpm2multiple interactionsEXP 6480464CTDAdenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Calcium affects the reaction [Hydrogen Peroxide promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Hydrogen Peroxide promotes the reaction [TRPM2 protein results in increased transport of Calcium]PMID:21900507
Trpm2increases transportISOTRPM2 (Homo sapiens)6480464CTDTRPM2 protein results in increased transport of CalciumPMID:12529379
Trpm2multiple interactionsISOTRPM2 (Homo sapiens)6480464CTD[Clotrimazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]; [Econazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]; TRPM2 protein affects the reaction [Mustard Gas results in increased abundance of Calcium]PMID:22036725
Trpm2multiple interactionsISOTrpm2 (Mus musculus)6480464CTDTRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium]; TRPM2 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium]PMID:20878536
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