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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311883
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trps1
Name: transcriptional repressor GATA binding 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trps1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of TRPS1 mRNAPMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998
Trps1increases expressionEXP 6480464CTDbisphenol A results in increased expression of TRPS1 mRNAPMID:29097150
Trps1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TRPS1 promoterPMID:23359474
Trps1affects methylationISOTrps1 (Mus musculus)6480464CTDbisphenol A affects the methylation of TRPS1 promoterPMID:27334623
Trps1increases expressionISOTRPS1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of TRPS1 mRNAPMID:29275510
Trps1increases expressionISOTrps1 (Mus musculus)6480464CTDbisphenol A results in increased expression of TRPS1 mRNAPMID:35479511
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