GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdc25c | decreases expression | ISO | CDC25C (Homo sapiens) | 6480464 | CTD | Doxorubicin results in decreased expression of CDC25C mRNA | PMID:30031762 PMID:36634904 | Cdc25c | increases response to substance | ISO | CDC25C (Homo sapiens) | 6480464 | CTD | CDC25C protein results in increased susceptibility to Doxorubicin | PMID:19074854 | Cdc25c | multiple interactions | ISO | CDC25C (Homo sapiens) | 6480464 | CTD | CDC25C protein inhibits the reaction [Doxorubicin results in increased expression of CDKN1A protein]; CDC25C protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]; CDC25C protein inhibits the reaction [Doxorubicin results in increased phosphorylation of CDK1 protein]; Doxorubicin results in increased phosphorylation of and results in decreased activity of CDC25C protein | PMID:17320279 PMID:19074854 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |