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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311693
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plscr4
Name: phospholipid scramblase 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plscr4affects expressionEXP 6480464CTDbisphenol A affects the expression of PLSCR4 mRNAPMID:25181051
Plscr4decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PLSCR4 mRNAPMID:34947998
Plscr4increases expressionEXP 6480464CTDbisphenol A results in increased expression of PLSCR4 mRNAPMID:33296240
Plscr4increases expressionISOPlscr4 (Mus musculus)6480464CTDbisphenol A results in increased expression of PLSCR4 mRNAPMID:30951980
Plscr4increases methylationISOPLSCR4 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of PLSCR4 genePMID:31601247
Plscr4multiple interactionsISOPLSCR4 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PLSCR4 mRNAPMID:28628672
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