Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311629
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dapk1
Name: death associated protein kinase 1
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:13231866480464CTDDecitabine affects the expression of DAPK1 mRNA

PMID:17133271
decreases methylationISORGD:13231866480464CTDDecitabine results in decreased methylation of DAPK1 promoter

PMID:17690560
increases expressionISORGD:13231866480464CTDDecitabine results in increased expression of DAPK1 mRNA

PMID:15924153, PMID:19037991, PMID:19215824
multiple interactionsISORGD:13231866480464CTDDecitabine inhibits the reaction [sodium arsenite results in decreased expression of DAPK1 protein]

PMID:19577553
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.