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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311392
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il17rb
Name: interleukin 17 receptor B
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il17rbdecreases expressionEXP 6480464CTDEstradiol results in decreased expression of IL17RB mRNAPMID:32145629
Il17rbincreases expressionISOIL17RB (Homo sapiens)6480464CTDEstradiol results in increased expression of IL17RB mRNAPMID:17121429 PMID:25321415 PMID:31614463
Il17rbincreases expressionISOIl17rb (Mus musculus)6480464CTDEstradiol results in increased expression of IL17RB mRNAPMID:23144751
Il17rbmultiple interactionsISOIL17RB (Homo sapiens)6480464CTD[Estradiol binds to ESR2 protein] which results in increased expression of IL17RB mRNA; [Estradiol co-treated with Progesterone] results in decreased expression of IL17RB mRNAPMID:20404318 PMID:20660070
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