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GENE - TERM ANNOTATION REPORT

RGD ID: 1311337
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pigc
Name: phosphatidylinositol glycan anchor biosynthesis, class C
Acc ID: GO:0000506
Term: glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
Definition: An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast.
Definition Source(s): GOC:kp, GOC:rb, PMID:10944123, PMID:15163411
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pigclocated_inISOPIGC (Homo sapiens)1624291RGD PMID:16162815

PMID:16162815
Pigcpart_ofISOPIGC (Homo sapiens)1624291RGD PMID:10944123 PMID:16162815

PMID:10944123 PMID:16162815
Pigcpart_ofIBAPANTHER:PTN000312400 or SGD:S000005997 or UniProtKB:Q925351600115GO_CentralGO_REF:0000033

GO_REF:0000033
Pigcpart_ofIEAPANTHER:PTHR12982:SF01600115TreeGrafterGO_REF:0000118

GO_REF:0000118
Pigcpart_ofISSUniProtKB:Q925351600115UniProtGO_REF:0000024

GO_REF:0000024
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