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GENE - TERM ANNOTATION REPORT

RGD ID: 1311217
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vcl
Name: vinculin
Acc ID: GO:0005856
Term: cytoskeleton
Definition: A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
Definition Source(s): GOC:mah, PMID:16959967, PMID:27419875
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vclis_active_inIBAMGI:98927 or PANTHER:PTN005285701 or Vcl (Rattus norvegicus) or UniProtKB:P12003 or WB:WBGene00000942 or dictyBase:DDB_G0273107 or dictyBase:DDB_G02814991600115GO_CentralGO_REF:0000033

GO_REF:0000033
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