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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310949
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sos1
Name: SOS Ras/Rac guanine nucleotide exchange factor 1
Acc ID: CHEBI:15996
Term: GTP
Definition: A purine ribonucleoside 5'-triphosphate that has formula C10H16N5O14P3.
Chemical ID: MESH:D006160
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sos1multiple interactionsISOSOS1 (Homo sapiens)6480464CTD[Enzyme Inhibitors binds to and results in decreased activity of SOS1 protein] inhibits the reaction [HRAS protein binds to Guanosine Triphosphate]PMID:25825487
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