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GENE - TERM ANNOTATION REPORT

RGD ID: 1310915
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mylk
Name: myosin light chain kinase
Acc ID: DOID:11394
Term: adult respiratory distress syndrome
Definition: A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia. (DO)
Definition Source(s): http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=adult+respiratory+distress+syndrome "DO" "DO", https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392788/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mylk ISOMYLK (Homo sapiens)4891491RGDDNA:missense mutations, silent mutation:CDS:p.H21P, p.P147S, p.T335T (human) 
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