GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tfap2a | affects response to substance | ISO | TFAP2A (Homo sapiens) | 6480464 | CTD | TFAP2A protein affects the susceptibility to Cisplatin | PMID:16217747 | Tfap2a | decreases expression | ISO | TFAP2A (Homo sapiens) | 6480464 | CTD | Cisplatin results in decreased expression of TFAP2A mRNA | PMID:25596134 | Tfap2a | increases expression | ISO | TFAP2A (Homo sapiens) | 6480464 | CTD | Cisplatin results in increased expression of TFAP2A protein | PMID:16204029 | Tfap2a | increases response to substance | ISO | TFAP2A (Homo sapiens) | 6480464 | CTD | TFAP2A protein results in increased susceptibility to Cisplatin | PMID:16204029 PMID:21489314 | Tfap2a | multiple interactions | ISO | TFAP2A (Homo sapiens) | 6480464 | CTD | [decitabine results in increased expression of TFAP2A protein] which results in increased susceptibility to Cisplatin; [TFAP2A protein co-treated with TP53 gene mutant form] results in decreased susceptibility to Cisplatin | PMID:16204029 PMID:21489314 | |
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