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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310158
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ripk1
Name: receptor interacting serine/threonine kinase 1
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ripk1multiple interactionsISORipk1 (Mus musculus)6480464CTD[Maneb co-treated with Paraquat] results in increased expression of RIPK1 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of RIPK1 mRNA]PMID:23963992
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